Apoptotic cell infusion treats ongoing collagen-induced arthritis, even in the presence of methotrexate, and is synergic with anti-TNF therapy.
Fiche publication
Date publication
août 2016
Journal
Arthritis research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Dr PERRUCHE Sylvain, Pr TOUSSIROT Eric
Tous les auteurs :
Bonnefoy F, Daoui A, Valmary-Degano S, Toussirot E, Saas P, Perruche S
Lien Pubmed
Résumé
Apoptotic cell-based therapies have been proposed to treat chronic inflammatory diseases. The aim of this study was to investigate the effect of intravenous (i.v.) apoptotic cell infusion in ongoing collagen-induced arthritis (CIA) and the interaction of this therapy with other treatments used in rheumatoid arthritis (RA), including methotrexate (MTX) or anti-TNF therapy.
Référence
Arthritis Res. Ther.. 2016 Aug;18(1):184