Homocitrulline as marker of protein carbamylation in hemodialyzed patients.
Fiche publication
Date publication
septembre 2016
Journal
Clinica chimica acta; international journal of clinical chemistry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLERY Philippe, Dr OUDART Jean-Baptiste
Tous les auteurs :
Jaisson S, Kazes I, Desmons A, Fadel F, Oudart JB, Santos-Weiss IC, Millart H, Touré F, Rieu P, Gillery P
Lien Pubmed
Résumé
Homocitrulline (HCit) is a carbamylation-derived product (CDP) that has been identified as a valuable biomarker of morbidity and mortality in patients with chronic kidney disease (CKD). The aim of this study was to determine whether initiation of hemodialysis therapy (HD) could induce variations of HCit concentrations in CKD patients.
Mots clés
Biomarkers, blood, Carbamates, metabolism, Citrulline, analogs & derivatives, Hemoglobin A, analogs & derivatives, Humans, Longitudinal Studies, Renal Dialysis, Renal Insufficiency, Chronic, blood
Référence
Clin. Chim. Acta. 2016 Sep;460:5-10