Respiratory Complications Lead to the Diagnosis of Chronic Granulomatous Disease in Two Adult Patients.
Fiche publication
Date publication
février 2017
Journal
Journal of clinical immunology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARTIN Thierry
Tous les auteurs :
Colin de Verdière S, Noel E, Lozano C, Catherinot E, Martin M, Rivaud E, Couderc LJ, Salvator H, Bustamante J, Martin T
Lien Pubmed
Résumé
Chronic granulomatous disease (CGD) is a primary immunodeficiency associated to multiple life-threatening bacterial and fungal infections, beginning in childhood. There are rare cases of diagnosis in adulthood. We describe here two cases of late diagnosis in adults: a 45-year-old woman and 59-year-old-man. CGD diagnosis should be considered in adult patients with unexplained infectious diseases with tissue granuloma.
Mots clés
CGD, NCF1, Pantoea, ROS, colitis, inflammatory bowel disease, pulmonary aspergillosis, pulmonary disease
Référence
J. Clin. Immunol.. 2017 Feb;37(2):113-116