Effect of nicotine on the proliferation and chondrogenic differentiation of the human Wharton's jelly mesenchymal stem cells.
Fiche publication
Date publication
janvier 2017
Journal
Bio-medical materials and engineering
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MAGDALOU Jacques, Dr VINCOURT Jean-Baptiste
Tous les auteurs :
Yang X, Qi Y, Avercenc-Leger L, Vincourt JB, Hupont S, Huselstein C, Wang H, Chen L, Magdalou J
Lien Pubmed
Résumé
Osteoarthritis (OA) is a chronic joint disease characterized by a progressive and irreversible degeneration of articular cartilage. Among the environmental risk factors of OA, tobacco consumption features prominently, although, there is a great controversy regarding the role of tobacco smoking in OA development. Among the numerous chemicals present in cigarette smoke, nicotine is one of the most physiologically active molecules.
Référence
Biomed Mater Eng. 2017 ;28(s1):S217-S228