Decreased Migration of Dendritic Cells into the Jugular-Nodose Ganglia by the CXCL12 Neutraligand Chalcone 4 in Ovalbumin-Sensitized Asthmatic Mice.
Fiche publication
Date publication
janvier 2017
Journal
Neuroimmunomodulation
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BONNET Dominique
Tous les auteurs :
Heck S, Daubeuf F, Le DD, Sester M, Bonnet D, Bals R, Frossard N, Dinh QT
Lien Pubmed
Résumé
The chemokine CXCL12 interacting with the CXC receptor 4 (CXCR4) has been reported to play a role in the development and progression of bronchial asthma, but its mechanism of action is still unknown. The objective of this study was to assess the effect of the CXCL12 neutraligand chalcone 4 on the migration of dendritic cells (DCs) in a murine model of allergic airway inflammation.
Référence
Neuroimmunomodulation. 2017 ;24(6):331-340