Cerebral 18F-FDG PET in macrophagic myofasciitis: An individual SVM-based approach.

Fiche publication


Date publication

janvier 2017

Journal

PloS one

Auteurs

Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine


Tous les auteurs :
Blanc-Durand P, Van Der Gucht A, Guedj E, Abulizi M, Aoun-Sebaiti M, Lerman L, Verger A, Authier FJ, Itti E

Résumé

Macrophagic myofasciitis (MMF) is an emerging condition with highly specific myopathological alterations. A peculiar spatial pattern of a cerebral glucose hypometabolism involving occipito-temporal cortex and cerebellum have been reported in patients with MMF; however, the full pattern is not systematically present in routine interpretation of scans, and with varying degrees of severity depending on the cognitive profile of patients. Aim was to generate and evaluate a support vector machine (SVM) procedure to classify patients between healthy or MMF 18F-FDG brain profiles.

Mots clés

Adult, Algorithms, Brain, diagnostic imaging, Fasciitis, diagnostic imaging, Female, Fluorodeoxyglucose F18, metabolism, Humans, Male, Middle Aged, Myositis, diagnostic imaging, Positron-Emission Tomography, methods, Predictive Value of Tests, Radiopharmaceuticals, metabolism, Support Vector Machine

Référence

PLoS ONE. 2017 ;12(7):e0181152