Biological Dosimetry Network in Africa: Establishment of a Dose-response Curve Using Telomere and Centromere Staining.
Fiche publication
Date publication
juin 2019
Journal
Health physics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr JEANDIDIER Eric
Tous les auteurs :
Soumboundou M, Nkengurutse I, Dossou J, Colicchio B, Djebou C, Gadji M, Houenon G, Dem A, Dedjan A, Diarra M, Adjibade R, Finot F, Hempel W, Dieterlen A, Jeandidier E, Rodriguez-Lafrasse C, M'kacher R
Lien Pubmed
Résumé
Biological dosimetry, based on the relationship between the absorbed dose after exposure to ionizing radiation and the frequency of scored aberrations, has been and continues to be an important tool for estimating the dose after exposure. Dicentric chromosomes are considered to be the most specific and sensitive aberration related to radiation exposure. Here, we established the dose-response curve following in vitro irradiation of circulating lymphocytes from healthy donors from three African countries after scoring unstable chromosomal aberrations.
Référence
Health Phys. 2019 Jun 6;: