Defining endoscopic response and remission in ulcerative colitis clinical trials: an international consensus.
Fiche publication
Date publication
mars 2017
Journal
Alimentary pharmacology & therapeutics
Auteurs
Membres identifiés du Cancéropôle Est :
Dr VUITTON Lucine, Pr PEYRIN-BIROULET Laurent
Tous les auteurs :
Vuitton L, Peyrin-Biroulet L, Colombel JF, Pariente B, Pineton de Chambrun G, Walsh AJ, Panes J, Travis SP, Mary JY, Marteau P
Lien Pubmed
Résumé
Recently, endpoints for clinical trials have been changing from measuring clinical response to mucosal healing in ulcerative colitis. Endoscopic evaluation is the current gold standard to assess mucosal lesions and has become a major measure of therapeutic efficacy in addition to patients reported outcomes.
Mots clés
Clinical Trials as Topic, methods, Colitis, Ulcerative, diagnosis, Consensus, Endoscopy, methods, Humans, Inflammatory Bowel Diseases, diagnosis, Internationality, Prospective Studies, Remission Induction, Severity of Illness Index, Treatment Outcome
Référence
Aliment. Pharmacol. Ther.. 2017 Mar;45(6):801-813