The roles of membranes and associated cytoskeleton in plant virus replication and cell-to-cell movement.
Fiche publication
Date publication
décembre 2017
Journal
Journal of experimental botany
Auteurs
Membres identifiés du Cancéropôle Est :
Dr HEINLEIN Manfred
Tous les auteurs :
Pitzalis N, Heinlein M
Lien Pubmed
Résumé
The infection of plants by viruses depends on cellular mechanisms that support the replication of the viral genomes, and the cell-to-cell and systemic movement of the virus via plasmodesmata (PD) and the connected phloem. While the propagation of some viruses requires the conventional endoplasmic reticulum (ER)-Golgi pathway, others replicate and spread between cells in association with the ER and are independent of this pathway. Using selected viruses as examples, this review re-examines the involvement of membranes and the cytoskeleton during virus infection and proposes potential roles of class VIII myosins and membrane-tethering proteins in controlling viral functions at specific ER subdomains, such as cortical microtubule-associated ER sites, ER-plasma membrane contact sites, and PD.
Mots clés
Actin, Tobacco mosaic virus, cytoskeleton, endoplasmic reticulum, membrane-tethering proteins, microtubules, movement protein, myosin, plant virus, plasma membrane, plasmodesmata
Référence
J. Exp. Bot.. 2017 12 18;69(1):117-132