Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy.
Fiche publication
Date publication
janvier 2015
Journal
PloS one
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CADIOT Guillaume, Dr VUITTON Lucine
Tous les auteurs :
Scialom S, Malamut G, Meresse B, Guegan N, Brousse N, Verkarre V, Derrieux C, Macintyre E, Seksik P, Savoye G, Cadiot G, Vuitton L, Marthey L, Carbonnel F, Cerf-Bensussan N, Cellier C
Lien Pubmed
Résumé
Anti-hypertensive treatment with the angiotensin II receptor antagonist olmesartan is a rare cause of severe Sprue-like enteropathy. To substantiate the hypothesis that olmesartan interferes with gut immune homeostasis, clinical, histopathological and immune features were compared in olmesartan-induced-enteropathy (OIE) and in autoimmune enteropathy (AIE).
Mots clés
Adolescent, Adult, Aged, Angiotensin II Type 1 Receptor Blockers, adverse effects, Diagnosis, Differential, Female, Gastrointestinal Diseases, chemically induced, Humans, Imidazoles, adverse effects, Male, Middle Aged, Polyendocrinopathies, Autoimmune, diagnosis, Tetrazoles, adverse effects, Young Adult
Référence
PLoS ONE. 2015 ;10(6):e0125024