From hemorheology to vascular mechanobiology: An overview.
Fiche publication
Date publication
janvier 2004
Journal
Clinical hemorheology and microcirculation
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BENSOUSSAN Danièle, Dr DUMAS Dominique, Pr BOURA Cédric
Tous les auteurs :
Muller S, Labrador V, Da Isla N, Dumas D, Sun R, Wang X, Wei L, Fawzi-Grancher S, Yang W, Traore M, Boura C, Bensoussan D, Eljaafari A, Stoltz JF
Lien Pubmed
Résumé
Almost all of the cells of the human body are subjected to mechanical stresses. In endothelial cells, mechanical stresses can vary from some milli-Pascal (shear stress) to one ore more Pascal (hydrostatic pressure). Now it is know that mechanical stresses have a decisive part cellular physiology. However, if the main biological effects of mechanical stress are well related, the mechanisms allowed the relation between mechanical stress to physiological phenomenon remain nearly unknown (mechanotransduction phenomenon). In this work, through personal results and published works, the authors considers all the effects of mechanical stresses and the possible hypothesis.
Mots clés
Blood Vessels, physiology, Endothelium, Vascular, cytology, Hemorheology, trends, Humans, Mechanotransduction, Cellular, physiology, Stress, Mechanical
Référence
Clin. Hemorheol. Microcirc.. 2004 ;30(3-4):185-200