Anxiolytics targeting GABA receptors: Insights on etifoxine.
Fiche publication
Date publication
janvier 2018
Journal
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr POISBEAU Pierrick
Tous les auteurs :
Poisbeau P, Gazzo G, Calvel L
Lien Pubmed
Résumé
Anxiety and adjustment disorders are among the most prevalent mental health conditions. This review focuses on γ-aminobutyric acid receptor type A (GABAR)-mediated anxiolysis, describing the action of both endogenous and exogenous modulators of GABAR. Future directions and innovative strategies to alleviate anxiety symptoms are discussed, with a particular emphasis on etifoxine.
Mots clés
Adjustment Disorders, drug therapy, Anti-Anxiety Agents, pharmacology, Anxiety Disorders, drug therapy, Humans, Oxazines, pharmacology, Receptors, GABA-A, drug effects
Référence
World J. Biol. Psychiatry. 2018 ;19(sup1):S36-S45