Noncoding RNA.
Fiche publication
Date publication
mars 2019
Journal
Microbiology spectrum
Auteurs
Membres identifiés du Cancéropôle Est :
Dr ROMBY Pascale
Tous les auteurs :
Desgranges E, Marzi S, Moreau K, Romby P, Caldelari I
Lien Pubmed
Résumé
Regulatory RNAs, present in many bacterial genomes and particularly in pathogenic bacteria such as , control the expression of genes encoding virulence factors or metabolic proteins. They are extremely diverse and include noncoding RNAs (sRNA), antisense RNAs, and some 5' or 3' untranslated regions of messenger RNAs that act as sensors for metabolites, tRNAs, or environmental conditions (e.g., temperature, pH). In this review we focus on specific examples of sRNAs of that illustrate how numerous sRNAs and associated proteins are embedded in complex networks of regulation. In addition, we discuss the CRISPR-Cas systems defined as an RNA-interference-like mechanism, which also exist in staphylococcal strains.
Référence
Microbiol Spectr. 2019 Mar;7(2):