Conformation changes in human hair keratin observed using confocal Raman spectroscopy after active ingredient application.
Fiche publication
Date publication
avril 2019
Journal
International journal of cosmetic science
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GOBINET Cyril, Pr PIOT Olivier
Tous les auteurs :
Essendoubi M, Meunier M, Scandolera A, Gobinet C, Manfait M, Lambert C, Auriol D, Reynaud R, Piot O
Lien Pubmed
Résumé
In hair care cosmetic products' evaluation, one commonly used method is to evaluate the hair appearance as a gold standard in order to determine the effect of an active ingredient on the final state of the hair via visual appreciation. Although other techniques have been proposed for a direct analysis of the hair fibres, they give only surface or structural information, without any accurate molecular information. A different approach based on confocal Raman spectroscopy has been proposed for tracking in situ the molecular change in the keratin directly in the human hair fibres. It presents a high molecular specificity to detect chemical interactions between molecules and can provide molecular information at various depths at the cortex and cuticle levels.
Mots clés
confocal Raman spectroscopy, hair care product, human hair treatment, keratin, molecular conformation
Référence
Int J Cosmet Sci. 2019 Apr 4;: