Evidence of Netosis in Septic Shock-Induced Disseminated Intravascular Coagulation.

Fiche publication


Date publication

mars 2017

Journal

Shock (Augusta, Ga.)

Auteurs

Membres identifiés du Cancéropôle Est :
Pr MAUVIEUX Laurent


Tous les auteurs :
Delabranche X, Stiel L, Severac F, Galoisy AC, Mauvieux L, Zobairi F, Lavigne T, Toti F, Anglès-Cano E, Meziani F, Boisramé-Helms J

Résumé

Neutrophils extracellular traps (NETs) have recently emerged as a new potential link between inflammation, immunity, and thrombosis and could play a key role in septic shock-induced disseminated intravascular coagulation (DIC) pathogenesis. The objective of our study was to investigate a potential link between NETosis and septic shock-induced DIC.

Mots clés

Adolescent, Adult, Aged, Aged, 80 and over, Disseminated Intravascular Coagulation, blood, Extracellular Traps, Female, Humans, Male, Middle Aged, Neutrophils, physiology, Nucleosomes, pathology, Prospective Studies, Shock, Septic, blood, Young Adult

Référence

Shock. 2017 Mar;47(3):313-317