Highly sensitive assessment of neuroblastoma minimal residual disease in ovarian tissue using RT-qPCR-A strategy for improving the safety of fertility restoration.
Fiche publication
Date publication
mai 2017
Journal
Pediatric blood & cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr AMIOT Clotilde
Tous les auteurs :
Grèze V, Brugnon F, Chambon F, Halle P, Canis M, Amiot C, Grémeau AS, Pereira B, Yáñez Peralta Y, Tchirkov A, Kanold J
Lien Pubmed
Résumé
Ovarian tissue cryopreservation (OTC) is the only option available to preserve fertility in prepubertal females with neuroblastoma (NB), a childhood solid tumor that can spread to the ovaries, with a risk of reintroducing malignant cells after an ovarian graft.
Mots clés
RT-qPCR, fertility preservation, minimal residual disease, neuroblastoma, ovarian tissue
Référence
Pediatr Blood Cancer. 2017 May;64(5):