FDG Brain PET/CT Revealing Bilateral Thalamostriatal Activation During a Symptomatic Episode in a Patient With Kleine-Levin Syndrome.
Fiche publication
Date publication
mai 2017
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine, Pr BOULAHDOUR Hatem
Tous les auteurs :
Drouet C, Morel O, Verger A, Guedj E, Boulahdour H
Lien Pubmed
Résumé
We report the case of a 14-year-old girl with clinically diagnosed Kleine-Levin syndrome. Electroencephalogram and brain MRI were unremarkable. An FDG PET/CT scan was acquired during a symptomatic episode, while she was asleep, and another PET scan was obtained when she was asymptomatic, awake, and quiet. Comparison of both examinations demonstrated a bilateral activation of thalami, caudate nuclei, and lenticular nuclei. These findings may be linked to the implication of thalamostriatal structures in the regulation of sleep and wakefulness.
Mots clés
Adolescent, Brain, diagnostic imaging, Female, Fluorodeoxyglucose F18, Humans, Kleine-Levin Syndrome, diagnostic imaging, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals
Référence
Clin Nucl Med. 2017 May;42(5):e261-e262