Evaluation of OSMOCELLS, a new semi-automatic device for osmotic fragility assessment.
Fiche publication
Date publication
mai 2017
Journal
International journal of laboratory hematology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr LESESVE Jean-François
Tous les auteurs :
Gérard D, Fattet AJ, Brakta C, Phulpin A, Steschenko D, Lesesve JF, Perrin J
Lien Pubmed
Résumé
The osmotic fragility (OF) test was a central test for the diagnosis of hereditary red blood cell (RBC) disorders (mostly hereditary spherocytosis (HS), but thalassaemia as well). Nowadays although the traditional multitubes method has lost a prominent place, many laboratories still perform such a laboured test, despite the lack of standardization. In fact, the evaluation of OF may offer an inexpensive screening for RBC disorders. We present a new semi-automatic device, allowing the continuous recording of OF, by an updated dialysis method.
Mots clés
haemolysis, osmocells, osmotic fragility, red blood cell disorders
Référence
Int J Lab Hematol. 2017 May;: