Hepatitis E Virus-Induced Primary Cutaneous CD30(+) T cell Lymphoproliferative Disorder.
Fiche publication
Date publication
août 2017
Journal
Journal of hepatology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HILLON Patrick
Tous les auteurs :
Mallet V, Bruneau J, Zuber J, Alanio C, Leclerc-Mercier S, Roque-Afonso AM, Kraft ARM, Couronné L, Roulot D, Wedemeyer H, Albert ML, Hillon P, Laroche L, Pol S, Hermine O
Lien Pubmed
Résumé
Several types of unexplained extra-hepatic manifestations, including haematological disorders, have been reported in the context of hepatitis E virus (HEV) infection. However, the underlying mechanism(s) of these manifestations are unknown. We provide evidence that HEV has an extra-hepatic endothelial tropism that can engage cutaneous T cells towards clonality.
Mots clés
CD30-positive cutaneous T cell lymphoproliferative disorder, Endothelial cell, Extra-hepatic manifestation, HEV, Hepatitis E, Lymphoma, Lymphomatoid papulosis, Non-Hodgkin lymphoma
Référence
J. Hepatol.. 2017 Aug;: