In vitro and in vivo potentialities for cartilage repair from human advanced knee osteoarthritis synovial fluid-derived mesenchymal stem cells.
Fiche publication
Date publication
novembre 2018
Journal
Stem cell research & therapy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre, Pr MAINARD Didier
Tous les auteurs :
Neybecker P, Henrionnet C, Pape E, Mainard D, Galois L, Loeuille D, Gillet P, Pinzano A
Lien Pubmed
Résumé
Mesenchymal stem cells (MSCs) are found in synovial fluid (SF) and can easily be harvested during arthrocentesis or arthroscopy. However, SF-MSC characterization and chondrogenicity in collagen sponges have been poorly documented as well as their hypothetical in vivo chondroprotective properties with intra-articular injections during experimental osteoarthritis (OA).
Mots clés
Cartilage, Collagen sponge, Stem cells, Synovial fluid, Tissue engineering
Référence
Stem Cell Res Ther. 2018 Nov 28;9(1):329