Modular laser-based endoluminal ablation of the gastrointestinal tract: in vivo dose-effect evaluation and predictive numerical model.
Fiche publication
Date publication
novembre 2018
Journal
Surgical endoscopy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MARESCAUX Jacques, Pr MUTTER Didier
Tous les auteurs :
Quero G, Saccomandi P, Kwak JM, Dallemagne B, Costamagna G, Marescaux J, Mutter D, Diana M
Lien Pubmed
Résumé
Endoscopic submucosal dissection allows for "en bloc" removal of early gastrointestinal neoplasms. However, it is technically demanding and time-consuming. Alternatives could rely on energy-based techniques. We aimed to evaluate a predictive numerical model of thermal damage to preoperatively define optimal laser settings allowing for a controlled ablation down to the submucosa, and the ability of confocal endomicroscopy to provide damage information.
Mots clés
Confocal endomicroscopy, Early gastrointestinal cancer, Laser ablation, Preclinical study, Predictive numerical model
Référence
Surg Endosc. 2018 Nov 19;: