Effectiveness of antibacterial prophylaxis in children with acute leukemia: A report from a single institution over a 20-year period.
Fiche publication
Date publication
octobre 2018
Journal
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr CHASTAGNER Pascal, Dr FOUYSSAC Fanny
Tous les auteurs :
Chastagner P, Michel D, Contet A, Lozniewski A, Hadou T, Schmitt C, Phulpin A, Fouyssac F, Mansuy L
Lien Pubmed
Résumé
Infection is the major cause of treatment-related mortality in childhood acute leukemia, mainly due to bacterial translocation across the intestinal mucosa. Only a few studies have reported the impact of different antibacterial prophylaxis treatments on digestive tract flora and infection-related mortality.
Mots clés
Acute leukemia, Antibacterial prophylaxis
Référence
Arch Pediatr. 2018 Oct 16;: