A cinnamon-derived procyanidin type A compound inhibits hepatitis C virus cell entry.
Fiche publication
Date publication
septembre 2017
Journal
Hepatology international
Auteurs
Membres identifiés du Cancéropôle Est :
Pr BAUMERT Thomas
Tous les auteurs :
Fauvelle C, Lambotin M, Heydmann L, Prakash E, Bhaskaran S, Vishwaraman M, Baumert TF, Moog C
Lien Pubmed
Résumé
Chronic hepatitis C virus (HCV) infection is a major cause of liver disease worldwide. Although direct-acting antivirals can cure the large majority of treated patients, important limitations remain, including treatment failure and high costs precluding access to therapy in resource-limited settings. We report herein the anti-HCV effects of IND02, a procyanidin type A molecule, isolated and characterized from cinnamon.
Mots clés
Antiviral, Hepatitis C, IND02, Infection, Liver
Référence
Hepatol Int. 2017 Sep;11(5):440-445