Global role for coactivator complexes in RNA polymerase II transcription.
Fiche publication
Date publication
octobre 2018
Journal
Transcription
Auteurs
Membres identifiés du Cancéropôle Est :
Dr DEVYS Didier, Dr TORA Laszlo
Tous les auteurs :
Fischer V, Schumacher K, Tora L, Devys D
Lien Pubmed
Résumé
SAGA and TFIID are related transcription complexes, which were proposed to alternatively deliver TBP at different promoter classes. Recent genome-wide studies in yeast revealed that both complexes are required for the transcription of a vast majority of genes by RNA polymerase II raising new questions about the role of coactivators.
Mots clés
RNA polymerase II, SAGA complex, TFIID complex, coactivator, nascent RNA
Référence
Transcription. 2018 Oct 9;:1-8