Genes and Pathways Regulated by Androgens in Human Neural Cells, Potential Candidates for the Male Excess in Autism Spectrum Disorder.
Fiche publication
Date publication
janvier 2018
Journal
Biological psychiatry
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MANDEL Jean-Louis
Tous les auteurs :
Quartier A, Chatrousse L, Redin C, Keime C, Haumesser N, Maglott-Roth A, Brino L, Le Gras S, Benchoua A, Mandel JL, Piton A
Lien Pubmed
Résumé
Prenatal exposure to androgens during brain development in male individuals may participate to increase their susceptibility to develop neurodevelopmental disorders such as autism spectrum disorder (ASD) and intellectual disability. However, little is known about the action of androgens in human neural cells.
Mots clés
Androgen receptor, Androgens, Autism spectrum disorder, Gene expression, Neural progenitor cells, Sex bias
Référence
Biol. Psychiatry. 2018 Jan 9;: