Galectin-3 pharmacological inhibition attenuates early renal damage in spontaneously hypertensive rats.
Fiche publication
Date publication
février 2018
Journal
Journal of hypertension
Auteurs
Membres identifiés du Cancéropôle Est :
Pr ROSSIGNOL Patrick
Tous les auteurs :
Martínez-Martínez E, Ibarrola J, Fernández-Celis A, Calvier L, Leroy C, Cachofeiro V, Rossignol P, López-Andrés N
Lien Pubmed
Résumé
The pharmacological blockade of galectin-3 (Gal-3), a β-galactoside-binding lectin, reduces renal impairment in acute kidney injury, hyperaldosteronism or nephropathy. We herein investigated the effects of pharmacological Gal-3 inhibition by modified citrus pectin (MCP) in renal damage in spontaneously hypertensive rats (SHRs).
Référence
J. Hypertens.. 2018 Feb;36(2):368-376