Investigation of cis-4-[F]Fluoro-D-Proline Uptake in Human Brain Tumors After Multimodal Treatment.
Fiche publication
Date publication
avril 2018
Journal
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine
Tous les auteurs :
Verger A, Stoffels G, Galldiks N, Lohmann P, Willuweit A, Neumaier B, Geisler S, Langen KJ
Lien Pubmed
Résumé
Cis-4-[F]fluoro-D-proline (D-cis-[F]FPro) has been shown to pass the intact blood-brain barrier and to accumulate in areas of secondary neurodegeneration and necrosis in the rat brain while uptake in experimental brain tumors is low. This pilot study explores the uptake behavior of D-cis-[F]FPro in human brain tumors after multimodal treatment.
Mots clés
Brain tumor, Cell death, Cis-4-[18F]fluoro-D-proline, PET, Treatment-related changes, [18F]FET
Référence
Mol Imaging Biol. 2018 Apr 23;: