Brain metabolism and related connectivity in patients with acrophobia treated by virtual reality therapy: an F-FDG PET pilot study sensitized by virtual exposure.
Fiche publication
Date publication
octobre 2018
Journal
EJNMMI research
Auteurs
Membres identifiés du Cancéropôle Est :
Pr VERGER Antoine
Tous les auteurs :
Verger A, Malbos E, Reynaud E, Mallet P, Mestre D, Pergandi JM, Khalfa S, Guedj E
Lien Pubmed
Résumé
The aim of this pilot study is to investigate the impact of virtual reality exposure therapy (VRET) on brain metabolism and connectivity. Eighteen patients with acrophobia were assessed by an F-FDG PET scan sensitized by virtual exposure before treatment, and nine of them were assessed again after eight sessions of VRET. Statistical Parametric Mapping was used to study the correlations between metabolism and pretherapeutic clinical scores and to compare metabolism before and after VRET (p voxel < 0.005, corrected for cluster volume). Metabolic connectivity was evaluated through interregional correlation analysis.
Mots clés
Acrophobia, Metabolic connectivity, PET, Virtual reality exposure therapy
Référence
EJNMMI Res. 2018 Oct 1;8(1):93