Antimicrobial peptide gene expression in periodontitis patients: A pilot study.
Fiche publication
Date publication
mai 2018
Journal
Journal of clinical periodontology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr VELARD Frédéric
Tous les auteurs :
Jourdain ML, Pierrard L, Kanagaratnam L, Velard F, Sergheraert J, Lefèvre B, Gangloff SC, Braux J
Lien Pubmed
Résumé
Antimicrobial peptides (AMPs) are one of the most active components of innate immunity and have characteristics that could place them at the heart of the pathogenesis of periodontal disease. This study investigated differences in the expression of AMP coding genes obtained using a simple harvesting technique, gingival smear, between two groups of patients: chronic periodontitis subjects versus healthy ones.
Mots clés
defensins, gene expression, innate immunity, periodontal disease
Référence
J. Clin. Periodontol.. 2018 May;45(5):524-537