Significant prevalence of mutations in incidentally discovered bilateral adrenal hyperplasia: results of the French MUTA-GR Study.
Fiche publication
Date publication
avril 2018
Journal
European journal of endocrinology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr HOEFFEL Christine
Tous les auteurs :
Vitellius G, Trabado S, Hoeffel C, Bouligand J, Bennet A, Castinetti F, Decoudier B, Guiochon-Mantel A, Lombes M, Delemer B,
Lien Pubmed
Résumé
Recently discovered mutations of gene, encoding for the GR, in patients with glucocorticoid resistance and bilateral adrenal incidentalomas prompted us to investigate whether GR mutations might be associated with adrenal hyperplasia.
Mots clés
Adrenal Gland Neoplasms, diagnostic imaging, Aged, Cells, Cultured, Female, Follow-Up Studies, France, epidemiology, Humans, Incidental Findings, Male, Middle Aged, Mutation, genetics, Prevalence, Receptors, Glucocorticoid, genetics
Référence
Eur. J. Endocrinol.. 2018 Apr;178(4):411-423