FDG PET findings of the brain in sudden blindness caused by bilateral central retinal artery occlusion revealing giant cell arteritis.
Fiche publication
Date publication
janvier 2015
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques, Pr IMPERIALE Alessio, Dr NOBLET Vincent
Tous les auteurs :
Dietemann S, Noblet V, Imperiale A, Blondet C, Namer IJ
Lien Pubmed
Résumé
We report the case of a 73-year-old woman presenting sudden blindness caused by bilateral simultaneous central retinal artery occlusion revealed by ophthalmoscopy. Temporal artery biopsy confirmed the giant cell arteritis. The patient was treated with a systemic steroid without visual recovery. FDG PET/CT was performed 6 months later in the context of persistent inflammatory syndrome. This case shows the close relationship between functional activity and glucose energy metabolism. We observed both bilateral occipital hypometabolism corresponding to loss of functional activity and bilateral temporal (auditory areas) and orbitofrontal hypermetabolism related to compensatory neuronal plasticity.
Mots clés
Aged, Blindness, diagnostic imaging, Brain, diagnostic imaging, Female, Fluorodeoxyglucose F18, Giant Cell Arteritis, diagnostic imaging, Humans, Multimodal Imaging, Positron-Emission Tomography, Radiopharmaceuticals, Retinal Artery Occlusion, complications, Tomography, X-Ray Computed
Référence
Clin Nucl Med. 2015 Jan;40(1):45-6