Pathological Laughing: Brain SPECT Findings.
Fiche publication
Date publication
septembre 2015
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques
Tous les auteurs :
Morland D, Wolff V, Blondet C, Marescaux C, Namer IJ
Lien Pubmed
Résumé
We present the case of a 40-year-old man consulting for uncontrollable episodes of laughing related to emotional lability and not systematically linked to feelings of happiness. Seven months earlier he had presented a pontine ischemic stroke related to an occlusion of the basilar and left vertebral arteries. No epileptic activity or new MRI brain lesions were found. Brain perfusion SPECT performed showed marked hypoperfusion in the right frontal inferior and temporoinsular regions, suggesting a diaschisis phenomenon caused by pontine lesions and highlighted laughing regulation pathways. The patient was successfully treated with a serotonergic reuptake inhibitor, fluoxetine.
Mots clés
Adult, Affective Symptoms, diagnostic imaging, Humans, Laughter, Male, Pons, diagnostic imaging, Stroke, complications, Tomography, Emission-Computed, Single-Photon
Référence
Clin Nucl Med. 2015 Sep;40(9):734-6