Spleen Uptake on Bone Scan After Frequent Platelet and RBC Transfusions.
Fiche publication
Date publication
octobre 2016
Journal
Clinical nuclear medicine
Auteurs
Membres identifiés du Cancéropôle Est :
Pr NAMER Izzie-Jacques, Pr FORNECKER Luc-Matthieu
Tous les auteurs :
De Marini P, Laplace A, Matuszak J, Fornecker LM, Namer IJ
Lien Pubmed
Résumé
A 21-year-old man, allogeneic hematopoietic stem cell transplantation recipient, was referred to our nuclear medicine department for a suspicion of knee osteonecrosis. Bone scan with Tc-HMDP did not show abnormal bone uptake but an intense spleen accumulation. F-FDG PET/CT performed on the same day showed no pathological spleen uptake. The patient had secondary hemochromatosis resulting from frequent transfusions in the setting of a chronic graft versus host disease with hemolysis and thrombocytopenia. The last RBC and platelet transfusions were performed 9 and 2 days before the examination, respectively. Secondary hemochromatosis and recent transfusions may explain our findings.
Mots clés
Bone and Bones, diagnostic imaging, Erythrocyte Transfusion, adverse effects, Fluorodeoxyglucose F18, Graft vs Host Disease, diagnostic imaging, Hematopoietic Stem Cell Transplantation, adverse effects, Humans, Male, Platelet Transfusion, adverse effects, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals, Spleen, diagnostic imaging, Technetium Tc 99m Medronate, analogs & derivatives, Young Adult
Référence
Clin Nucl Med. 2016 Oct;41(10):802-3