Neuromuscular Blocking Agents induced anaphylaxis: Results and trends of a French Pharmacovigilance survey from 2000 to 2012.
Fiche publication
Date publication
avril 2018
Journal
Allergy
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GILLET Pierre
Tous les auteurs :
Petitpain N, Argoullon L, Masmoudi K, Fedrizzi S, Cottin J, Latarche C, Mertes PM, Gillet P,
Lien Pubmed
Résumé
Perioperative anaphylaxis mainly involves neuromuscular blocking agents (NMBAs) with an IgE mediated mechanism. In France, this life threatening condition is fairly reported by anesthetists and allergologists, and two safety alerts concerning suxamethonium were raised in 2011 and 2012. This led to start a national survey over the 2000-2012 period which objectives were to provide a descriptive analysis, to estimate incidence rates and to analyze the trends over this period.
Mots clés
Incidence, anaphylaxis, neuromuscular blocking agents, rocuronium, suxamethonium
Référence
Allergy. 2018 Apr 13;: