Development of a porcine beating-heart model of self-myocardial retroperfusion: evaluation of hemodynamic and cardiac responses to ischemia and clinical applications.
Fiche publication
Date publication
juin 2018
Journal
The Journal of cardiovascular surgery
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GAUCHOTTE Guillaume
Tous les auteurs :
Grandmougin D, Casse JM, Chalon A, Luo Y, Falanga A, Marie V, Groubatch-Joineau F, Mourer B, Grandmougin M, Grandmougin D, Gauchotte G, Maureira JP, Tran N
Lien Pubmed
Résumé
Retrograde perfusion into the coronary sinus is used to deliver cardioplegia. We developed an in-vivo porcine beating-heart model of self-myocardial retroperfusion (SMR) using the venous route to supply myocardial oxygenation and sought to assess hemodynamic and cardiac responses triggered by SMR before and after a prolonged occlusion of the LAD.
Mots clés
Animals, Aorta, physiopathology, Coronary Circulation, Coronary Sinus, physiopathology, Disease Models, Animal, Echocardiography, Doppler, Hemodynamics, Male, Myocardial Contraction, Myocardial Ischemia, blood, Oxygen, blood, Perfusion, adverse effects, Stroke Volume, Sus scrofa, Time Factors, Ventricular Function, Left
Référence
J Cardiovasc Surg (Torino). 2018 Jun;59(3):438-452