Triple-negative and HER2-overexpressing breast cancer cell sialylation impacts tumor microenvironment T-lymphocyte subset recruitment: a possible mechanism of tumor escape.
Fiche publication
Date publication
janvier 2018
Journal
Cancer management and research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GARBAR Christian, Pr MERROUCHE Yacine, Pr BENSUSSAN Armand
Tous les auteurs :
Garbar C, Mascaux C, Merrouche Y, Bensussan A
Lien Pubmed
Résumé
Breast cancers develop different patterns of sialylation to modulate their tumor-infiltrating lymphocyte (TIL) environment. We studied the relationship between α-2,6 sialyltransferases and the TIL in different breast cancer molecular subgroups.
Mots clés
HER2, breast, carcinoma, sialyltransferase, triple-negative
Référence
Cancer Manag Res. 2018 ;10:1051-1059