A Population Study of Common Ocular Abnormalities in C57BL/6N rd8 Mice.
Fiche publication
Date publication
mai 2018
Journal
Investigative ophthalmology & visual science
Auteurs
Membres identifiés du Cancéropôle Est :
Dr HERAULT Yann
Tous les auteurs :
Moore BA, Roux MJ, Sebbag L, Cooper A, Edwards SG, Leonard BC, Imai DM, Griffey S, Bower L, Clary D, Lloyd KCK, Hérault Y, Thomasy SM, Murphy CJ, Moshiri A
Lien Pubmed
Résumé
The purpose of this study was to quantify the frequency and severity of ocular abnormalities affecting wild-type C57BL/6N mice, the most common strain used worldwide for the creation of single-gene knockouts.
Mots clés
Animals, Anterior Eye Segment, pathology, DNA, genetics, DNA Mutational Analysis, Disease Models, Animal, Eye Abnormalities, diagnosis, Intraocular Pressure, physiology, Male, Mice, Mice, Inbred C57BL, Mutation, Nuclear Proteins, genetics, Ophthalmoscopy, Posterior Eye Segment, pathology, Tomography, Optical Coherence
Référence
Invest. Ophthalmol. Vis. Sci.. 2018 May 1;59(6):2252-2261