[Conformal radiotherapy for vertebral bone metastasis].
Fiche publication
Date publication
octobre 2016
Journal
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
Auteurs
Membres identifiés du Cancéropôle Est :
Dr FAIVRE Jean-Christophe
Tous les auteurs :
Faivre JC, Py JF, Vogin G, Martinage G, Salleron J, Royer P, Grandgirard N, Pasquier D, Thureau S
Lien Pubmed
Résumé
Analgesic external beam radiation therapy is a standard of care for patients with uncomplicated painful bone metastases and/or prevention of bone complications. In case of fracture risk, radiation therapy is performed after surgery in a consolidation of an analgesic purpose and stabilizing osteosynthesis. Radiotherapy is mandatory after vertebroplasty or kyphoplasty. Spinal cord compression - the only emergency in radiation therapy - is indicated postoperatively either exclusively for non surgical indication. Analgesic re-irradiation is possible in the case of insufficient response or recurrent pain after radiotherapy. Metabolic radiation, bisphosphonates or denosumab do not dissuade external radiation therapy for pain relief. Systemic oncological treatments can be suspended with a period of wash out given the risk of radiosensitization or recall phenomenon. Better yet, the intensity modulated radiotherapy and stereotactic radiotherapy can be part of a curative strategy for oligometastatic patients and suggest new treatment prospects.
Mots clés
Back Pain, etiology, Decompression, Surgical, Humans, Organs at Risk, Patient Education as Topic, Quality of Life, Radiotherapy, Conformal, Radiotherapy, Image-Guided, Spinal Cord Compression, etiology, Spinal Neoplasms, complications
Référence
Cancer Radiother. 2016 Oct;20(6-7):493-9