Clinical, dermoscopic, histological and molecular analysis of BAP1 inactivated melanocytic nevus/tumor in two familial cases of BAP1 syndrome.
Fiche publication
Date publication
mai 2018
Journal
The British journal of dermatology
Auteurs
Membres identifiés du Cancéropôle Est :
Dr GRANEL-BROCARD Florence
Tous les auteurs :
Moawad S, Reigneau M, de la Fouchardière A, Soufir N, Schmutz JL, Granel-Brocard F, Phan A, Bursztejn AC
Lien Pubmed
Résumé
BRCA1 associated protein (BAP)1-inactivated melanocytic nevus/tumours (BIMN/Ts) are specific skin tumours that appear during the first two decades of life. These lesions must be recognized by dermatologists and pathologists as an early predictive marker of BAP1 cancer syndrome, as they may precede the development of uveal and cutaneous melanomas, mesotheliomas, lung adenocarcinomas, renal cell carcinomas, and meningiomas by several years. The dermoscopic characteristics of these tumours have not been described. This article is protected by copyright. All rights reserved.
Référence
Br. J. Dermatol.. 2018 May 13;: