Neutrophilic urticarial dermatosis: A review.
Fiche publication
Date publication
septembre 2018
Journal
Annales de dermatologie et de venereologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr LIPSKER Dan
Tous les auteurs :
Gusdorf L, Lipsker D
Lien Pubmed
Résumé
Neutrophilic urticarial dermatosis (NUD) is a rare form of dermatosis. In clinical terms, it consists of a chronic or recurrent eruption comprising slightly elevated, pink to reddish plaques or macules. The elementary lesion lasts 24 to 48hours and resolves without leaving any residual pigmentation. Extra-cutaneous signs are common, particularly fever or arthralgia. At histopathology, the dermis contains dense neutrophilic interstitial infiltrate with leukocytoclasis, but without fibrinoid necrosis of vessel walls. NUD often occurs in a setting of underlying systemic disease. The most commonly associated diseases are adult-onset Still's disease, Schnitzler syndrome, lupus erythematosus and cryopyrin-associated periodic syndromes. Treatment of NUD depends on the clinical context. Dapsone and colchicine are often effective.
Mots clés
Adult-onset Still's disease, Dermatose neutrophilique, Dermatose neutrophilique urticarienne, Lupus erythematosus, Lupus érythémateux, Maladie de Still de l’adulte, Neutrophilic dermatosis, Neutrophilic urticarial dermatosis, Schnitzler syndrome, Syndrome de Schnitzler, Urticaire, Urticaria
Référence
Ann Dermatol Venereol. 2018 Sep 14;: