Systematic review and network meta-analysis of clinical outcomes associated with isavuconazole versus relevant comparators for patients with invasive aspergillosis.

Fiche publication


Date publication

juillet 2018

Journal

Current medical research and opinion

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HERBRECHT Raoul


Tous les auteurs :
Herbrecht R, Kuessner D, Pooley N, Posthumus J, Escrig C

Résumé

Voriconazole, amphotericin B (AmB) formulations, and isavuconazole are all included in guideline recommendations for treatment of patients with invasive aspergillosis (IA) but the relative efficacy of isavuconazole versus AmB formulations has not been directly compared. We aimed to estimate the relative efficacy of isavuconazole compared with AmB deoxycholate (AmB-D), liposomal AmB (L-AmB), and voriconazole for the treatment of patients with proven/probable IA.

Mots clés

Amphotericin B, invasive aspergillosis, isavuconazole, network meta-analysis, voriconazole

Référence

Curr Med Res Opin. 2018 Jul 19;:1-21