KRAS-specific Amino Acid Substitutions are Associated With Different Responses to Chemotherapy in Advanced Non-small-cell Lung Cancer.
Fiche publication
Date publication
août 2018
Journal
Clinical lung cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Dr BEAU-FALLER Michèle, Pr CHENARD Marie-Pierre, Pr FALCOZ Pierre-Emmanuel, Dr MENNECIER Bertrand
Tous les auteurs :
Renaud S, Guerrera F, Seitlinger J, Reeb J, Voegeli AC, Legrain M, Mennecier B, Santelmo N, Falcoz PE, Quoix E, Chenard MP, Weingertner N, Beau-Faller M, Massard G
Lien Pubmed
Résumé
Emerging data highlight different clinical behaviors according to KRAS amino acid substitutions (AASs) in patients with non-small-cell lung cancer (NSCLC). We aimed to evaluate whether different KRAS AASs were associated with different responses to chemotherapy.
Mots clés
Amino-acid substitution, Chemotherapy, KRAS, Lung cancer, Response
Référence
Clin Lung Cancer. 2018 Aug 22;: