Hypogammaglobulinemia associated with gold therapy: evidence for a partial maturation blockade of B cells.
Fiche publication
Date publication
octobre 1987
Journal
The Journal of rheumatology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis
Tous les auteurs :
Guillemin F, Bene MC, Aussedat R, Bannwarth B, Pourel J
Lien Pubmed
Résumé
Extensive immunological investigations were performed in a patient with definite seronegative rheumatoid arthritis who developed hypogammaglobulinemia in the course of gold therapy. The data obtained suggest the presence of acquired maturation abnormalities in the B cell compartment.
Mots clés
Agammaglobulinemia, chemically induced, Anti-Inflammatory Agents, adverse effects, Arthritis, Rheumatoid, drug therapy, B-Lymphocytes, drug effects, Dimercaprol, adverse effects, Humans, Lymphocyte Activation, drug effects, Male, Metalloproteins, adverse effects, Middle Aged, Organogold Compounds, Organometallic Compounds, Propanols, Steroids, Sulfhydryl Compounds
Référence
J. Rheumatol.. 1987 Oct;14(5):1034-5