Superficial vein thrombosis, thrombin generation and activated protein C resistance as predictors of thromboembolic events in lupus and antiphospholipid patients. A prospective cohort study.
Fiche publication
Date publication
juillet 2013
Journal
Thrombosis research
Auteurs
Membres identifiés du Cancéropôle Est :
Dr RAT Anne-Christine
Tous les auteurs :
Zuily S, Regnault V, Guillemin F, Kaminsky P, Rat AC, Lecompte T, Wahl D
Lien Pubmed
Résumé
Predicting thrombosis in patients with systemic lupus erythematosus (SLE) and/or antiphospholipid antibodies (aPL) is still challenging. Our objective was to determine risk factors for thrombotic events including activated protein C (APC) resistance proven by a thrombin generation (TG) assay in patients with SLE and/or aPL.
Mots clés
Activated Protein C Resistance, complications, Antibodies, Antiphospholipid, analysis, Antiphospholipid Syndrome, complications, Cohort Studies, Female, Follow-Up Studies, Humans, Lupus Erythematosus, Systemic, complications, Male, Prognosis, Risk Factors, Thrombin, metabolism, Venous Thrombosis, complications
Référence
Thromb. Res.. 2013 Jul;132(1):e1-7