Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial.
Fiche publication
Date publication
octobre 2016
Journal
The Lancet. Neurology
Auteurs
Membres identifiés du Cancéropôle Est :
Pr GUILLEMIN Francis, Pr MOULIN Thierry
Tous les auteurs :
Bracard S, Ducrocq X, Mas JL, Soudant M, Oppenheim C, Moulin T, Guillemin F,
Lien Pubmed
Résumé
Intravenous thrombolysis with alteplase alone cannot reperfuse most large-artery strokes. We aimed to determine whether mechanical thrombectomy in addition to intravenous thrombolysis improves clinical outcome in patients with acute ischaemic stroke.
Mots clés
Aged, Brain Ischemia, diagnostic imaging, Combined Modality Therapy, Female, Fibrinolytic Agents, administration & dosage, Humans, Male, Mechanical Thrombolysis, methods, Middle Aged, Outcome Assessment (Health Care), Stroke, diagnostic imaging, Tissue Plasminogen Activator, administration & dosage
Référence
Lancet Neurol. 2016 10;15(11):1138-47