[Inflammatory myofibroblastic tumor of the lung with endobronchial, infiltrating, multifocal and recurrent form].
Fiche publication
Date publication
janvier 1995
Journal
Annales de pathologie
Auteurs
Membres identifiés du Cancéropôle Est :
Pr MERLIN Jean-Louis
Tous les auteurs :
Boman F, Champigneulle J, Boccon-Gibod L, Merlin JL, De Miscault G, Schmitt C, Sommelet D, Floquet J
Lien Pubmed
Résumé
Pulmonary inflammatory myofibroblastic tumor (inflammatory pseudotumor, plasma cell granuloma) was reported most often as a single peripheral mass, successfully cured by surgery. A 14-year-old girl presented with a large left pulmonary mass involving and obliterating the main bronchus; there were angioinvasion and infiltration of mediastinum, hilar lymph nodes and pleura. Multiple, often tiny nodules were seen in the right lung. At microscopic examination, there were lymphocytic and plasmacytic infiltrates and borderline myofibroblastic proliferation with focal nuclear anaplasia. Smaller lesions were similar to organizing pneumonia. Disease was progressive in the remaining right lung after surgical resection and a two-month treatment with corticoids. The patient was then treated with chemotherapy. She was alive and well (twenty-month follow-up).
Mots clés
Adolescent, Bronchial Neoplasms, pathology, Female, Humans, Neoplasm Invasiveness, Neoplasm Recurrence, Local, pathology, Neoplasms, Multiple Primary, pathology, Plasma Cell Granuloma, Pulmonary, pathology
Référence
Ann Pathol. 1995 ;15(3):207-10