Apoptosis participates to liver damage in HSV-induced fulminant hepatitis.

Fiche publication


Date publication

décembre 2003

Journal

Apoptosis : an international journal on programmed cell death

Auteurs

Membres identifiés du Cancéropôle Est :
Pr PRETET Jean-Luc


Tous les auteurs :
Prétet JL, Pelletier L, Bernard B, Coumes-Marquet S, Kantelip B, Mougin C

Résumé

HSV fulminant hepatitis is a rare pathology. Rapid hepatic failure, as a consequence of extended liver damage, has generally been attributed to necrosis. As apoptosis can constitute another way for hepatocytes to die, we decided to investigate whether programmed cell death took place during HSV fulminant hepatitis.

Mots clés

Apoptosis, physiology, Biomarkers, Hepatocytes, pathology, Humans, Liver, pathology, Liver Failure, pathology, Simplexvirus, pathogenicity

Référence

Apoptosis. 2003 Dec;8(6):655-63