Can treatment with Cocculine improve the control of chemotherapy-induced emesis in early breast cancer patients? A randomized, multi-centered, double-blind, placebo-controlled Phase III trial.
Fiche publication
Date publication
décembre 2012
Journal
BMC cancer
Auteurs
Membres identifiés du Cancéropôle Est :
Pr PIVOT Xavier
Tous les auteurs :
Pérol D, Provençal J, Hardy-Bessard AC, Coeffic D, Jacquin JP, Agostini C, Bachelot T, Guastalla JP, Pivot X, Martin JP, Bajard A, Ray-Coquard I
Lien Pubmed
Résumé
Chemotherapy induced nausea and vomiting (CINV) remains a major problem that seriously impairs the quality of life (QoL) in cancer patients receiving chemotherapy regimens. Complementary medicines, including homeopathy, are used by many patients with cancer, usually alongside with conventional treatment. A randomized, placebo-controlled Phase III study was conducted to evaluate the efficacy of a complex homeopathic medicine, Cocculine, in the control of CINV in non-metastatic breast cancer patients treated by standard chemotherapy regimens.
Mots clés
Adult, Aged, Antiemetics, therapeutic use, Antineoplastic Agents, adverse effects, Breast Neoplasms, complications, Double-Blind Method, Female, Humans, Middle Aged, Morphinans, therapeutic use, Plant Extracts, therapeutic use, Quality of Life, Vomiting, chemically induced, Young Adult
Référence
BMC Cancer. 2012 Dec;12:603