[An appreciation of maternal smoking with high-performance liquid chromatographic determination of maternal and neonatal urinary cotinine]
Fiche publication
Date publication
avril 2001
Auteurs
Membres identifiés du Cancéropôle Est :
Dr WORONOFF Anne-Sophie
Tous les auteurs :
Burguet A, Berard M, Woronoff AS, Roth P, Menetrier M, Vanlemmens P, Schaal JP, Menget A
Lien Pubmed
Résumé
OBJECTIVE: To study the correlation of urinary cotinine levels in mothers and newborns with the number of cigarettes smoked at the end of pregnancy. Population and methods. We recorded the smoking habits of 123 mothers attending a university maternity clinic and measured urinary cotitine levels in mothers and their newborns. All mothers were Europeans and gave birth to a normal full-term (37 weeks gestation) infant. Cotinine levels were measured with high-performance liquid chromatography from urine samples taken during the 6-hour period prior to or after delivery for the mothers and 24-h after birth for the newborns. RESULTS: The average cotinine level for non-smoking mothers, for those who smoked one to nine cigarettes a day and heavy smokers (ten or more cigarettes per day) were 0.21, 2.17 and 4.28 mol/l respectively (p
Référence
J Gynecol Obstet Biol Reprod (Paris). 2001 Apr;30(2):166-73.