Improvement of the LLS and MAP deconvolution algorithms by automatic determination of optimal regularization parameters and pre-filtering of original data.

Fiche publication


Date publication

janvier 2005

Auteurs

Membres identifiés du Cancéropôle Est :
Pr HAEBERLE Olivier


Tous les auteurs :
Colicchio B, Haeberle O, Xu C, Dieterlen A, Jung G

Résumé

We show that automatic determination of regularization threshold and pre-filtering of 3-D fluorescence microscopic images improves the stability of deconvolution results when using the Linear Least squares Solution or the Maximum a Posteriori method. Doing so, the choice of the regularization parameter much less depends on a priori knowledge of the specimen or skills of the operator. This increases the reliability and repeatability of quantitative measurements on deconvolved images. (C) 2004 Elsevier B.V. All rights reserved.

Référence

Opt Commun. 2005 Jan 3;244(1-6):37-49.